منابع مشابه
Behavioral tagging of extinction learning.
Extinction of contextual fear in rats is enhanced by exposure to a novel environment at 1-2 h before or 1 h after extinction training. This effect is antagonized by administration of protein synthesis inhibitors anisomycin and rapamycin into the hippocampus, but not into the amygdala, immediately after either novelty or extinction training, as well as by the gene expression blocker 5,6-dichloro...
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Decline in cognitive functions, including hippocampus-dependent spatial memory, is commonly observed at a later stage of aging (e.g., >20 months old in rodents) and typically studied after a discrete learning event. How normal aging, particularly at an early stage, affects the modulatory aspect of memory persistence is underinvestigated. Previous studies in young animals show that weak, fading ...
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In noisy, dynamic environments, organisms must distinguish genuine change (e.g., the movement of prey) from noise (e.g., the rustling of leaves). Expectations should be updated only when the organism believes genuine change has occurred. Although individual variables can be highly unreliable, organisms can take advantage of the fact that changes tend to be correlated (e.g., movement of prey wil...
متن کاملOrganized behavioral responses to lateral hypothalamic electrical stimulation in infant rats.
Brief trains of electrical stimulation (500 msec) were administered to 3-, 6-, 10-, and 15-day-old rat pups through electrodes directed at the medical forebrain bundle (MFB) at the level of the lateral hypothalamus. Stimulation was given at three different frequencies: once per 30 sec, once per 20 sec, and once per 10 sec. Pups 10 days of age and younger became behaviorally activated by stimula...
متن کاملSleep homeostasis in infant rats.
Homeostatic regulation is a defining characteristic of sleep but has rarely been examined in infants. This study presents an automated method of sleep deprivation in which 5-day-old rats were shocked whenever the nuchal muscle became atonic. The intensity of shock was always set at the minimal level required to maintain arousal. Deprived pups exhibited rapid increases in sleep pressure, as evid...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2018
ISSN: 1549-5485
DOI: 10.1101/lm.047605.118